Grafe Fruit Extract (Vitis vinifera) as an antioxidant

Authors

  • Hartono Public Health Department, Faculty Of Medicine Universitas Prima Indonesia Medan, Indonesia
  • I Nyoman Ehrich Lister Public Health Department, Faculty Of Medicine Universitas Prima Indonesia Medan, Indonesia
  • Buter Samin Public Health Department, Faculty Of Medicine Universitas Prima Indonesia Medan, Indonesia

DOI:

https://doi.org/10.51601/ijhp.v2i1.12

Keywords:

Vitis vinivera, antioksidan, DPPH, ABTS, LC-MS/MS

Abstract

One plant that is believed to have anti-diabetic effects is grapes (Vitis vinifera), which contains polyphenol compounds. The antioxidant and anti-postprandial hyperglycemics of grape extract show potential in treating diabetes. This study is an experimental study that aims to explore grape extract extracts as antioxidants through testing (DPPH, ABTS, LC-MS/MS). Based on the test results, grape extract contains very high phytochemicals, including terpenoids and alkaloids, and antioxidant test results found DPPH with an average IC50 value of 21.49 g / mL and at the lowest concentration (6.25 g / mL). The GFE also showed the highest antioxidant activity against ABTS trapping with an average IC50 value of 74.07 g/mL and LC-MS/MS results obtained grape extract samples containing 0.00001% chlorogenic acid and querce-tin compounds of 0.00012%.

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Published

2022-02-06

How to Cite

Hartono, I Nyoman Ehrich Lister, & Buter Samin. (2022). Grafe Fruit Extract (Vitis vinifera) as an antioxidant. International Journal of Health and Pharmaceutical (IJHP), 2(1), 53–56. https://doi.org/10.51601/ijhp.v2i1.12