The Relationship Between Smoking And The Formation Of Lung Cavity Lesions In Tuberculosis Patients At H Adam Malik General Hospital
DOI:
https://doi.org/10.51601/ijhp.v4i4.291Abstract
The purpose of this study is to ascertain whether smoking has any connection to the development of lung cavity lesions in tuberculosis patients at H Adam Malik General Hospital. This study is an observational, analytical, case-control investigation. In this investigation, 80 samples total 40 individuals who smoked and 40 non-smokers were used. How to choose a sample using the purposive sampling method. Information was gleaned from the medical files of H Adam Malik General Hospital's tuberculosis patients in 2021. The Chi Square test was used to examine the research data. According to the study's findings, 62.5% of the research sample's participants were men and 37.5% were women. The majority 28.7% are in the 46 to 55-year-old age range. According to the Brinkman Index, up to 28.8% of the sample's participants were heavy smokers. Lung cavity lesions are present in 46.25 percent of patients, as may be shown. Up to 30% of patients who smoke have lung cavity lesions. According to the analysis's findings, smoking was associated with the development of lung cavity lesions in tuberculosis patients at Adam Malik General Hospital with a value of p = 0.014 (p 0.05), and those patients who smoked had a risk of developing lung cavity lesions that was 3.115 times higher (OR = 3.115). This study's findings suggest that smokers with tuberculosis are three times more likely to develop lung cavity lesions.
References
World Health Organization. Global Tuberculosis Report. 2022.
Kementrian Kesehatan RI. Dashboard Tuberkulosis Indonesia [Internet]. 2022. Available from: https://tbindonesia.or.id/pustaka-tbc/dashboard-tb/
Kementrian Kesehatan RI. Riset Kesehatan Dasar 2013. Jakarta; 2013. 132–138 p.
Kementrian Kesehatan RI. Riset Kesehatan Dasar 2018. 2018. 324–342 p
Dinas Kesehatan Provinsi Sumatera Utara. Profil Kesehatan Provinsi Sumatera Utara. 2019. 148–153 p.
World Health Organization. Global Tuberculosis Report. 2021. 7–9 p.
Kementrian Kesehatan RI. Pusat Data dan Informasi Kementerian Kesehatan RI - Tuberkulosis. Jakarta; 2018. 1–10 p.
World Health Organization. Tobacco. 2021; Available from: https://www.who.int/news-room/fact-sheets/detail/tobacco
The Tobacco Atlas. Tobacco Death in Indonesia [Internet]. 2016. Available from: https://tobaccoatlas.org/country/indonesia/
Situngkir JD, Damanik I, Siahaan JM. Perbandingan Sputum BTA Positif dan Sputum BTA Negatif Terhadap Foto Toraks Pada Pasien TB Paru. J Kedokt Methodist. 2019;12:22–7.
Pradana RF, Nawawi YS, Satoto B. Evaluasi Lesi Kavitas dengan Foto Toraks pada Pasien MDR-TB Pulmoner. e-Journal Kedokt Indones. 2018;6:118–22.
Kim S-H, Shin YM, Yoo JY, Cho JY, Kang H, Lee H, et al. Clinical Factors Associated with Cavitary Tuberculosis and Its Treatment Outcomes. J Pers Med. 2021;11(11):1081.
Altet N, Latorre I, Jimenez-Fuentes MA, Maldonado J, Molina I, Gonzalez-Dıaz Y, et al. Assessment of the influence of direct tobacco smoke on infection and active TB management. PLoS One. 2017;12(8).
Putri YN. Hubungan Riwayat Merokok Dengan Gambaran Lesi Foto Toraks Pasien Tuberkulosis Paru Di Ruang Pelayanan Tuberkulosis Terpadu RSUDZA Banda Aceh. Universitas Syiah Kuala; 2016.
Pratana RI. Hubungan Kebiasaan dan Riwayat Merokok Dengan Keberadaan Lesi Kavitas Paru Pada Pasien Tuberkulosis. Universitas Indonesia; 2018.
Raviglione MC. Tuberculosis. In: Harrison’s Principles of Internal Medicine. 20th ed. 2018. p. 1236–58.
Amin Z, Bahar A. Tuberkulosis Paru. In: Setiati S, Alwi I, Sudoyo AW, K MS, Setiyohadi B, Syam AF, editors. BUKU AJAR ILMU PENYAKIT DALAM. 6th ed. Jakarta: Interna Publishing; 2014. p. 863–72.
Bustan MN. Epidemiologi Penyakit Tidak Menular. Jakarta; 2015. 204–212 p.
Aditama TY. Rokok dan Kesehatan. 3rd ed. Jakarta: Penerbit Universitas Indonesia; 2011. 18–46 p.
Djojodibroto RD. Respirologi (Respiratory Medicine). 2nd ed. Suyono YJ, Melinda E, editors. Jakarta: EGC; 2014. 86–92 p.
Urbanowski ME, Ordonez AA, Ruiz-Bedoya CA, Jain SK, Bishai WR. Cavitary Tuberculosis : The Gateway of Disease Transmission. Lancet Infect Dis. 2021;20(6):117–28.
Strzelak A, Ratajczak A, Adamiec A, Feleszko W. Tobacco Smoke Induces and Alters Immune Responses in the Lung Triggering Inflammation, Allergy, Asthma and Other Lung Diseases: A Mechanistic Review. Int J Environ Res Public Health. 2018;15(5):1–35.
Gadkowski L, Stout J. Cavitary Pulmonary Disease. Clin Microbiol Reveiws. 2008;21(2):305–33.
Parkar AP, Kandiah P. Differential Diagnosis of Cavitary Lung Lesions. J Belgian Soc Radiol. 2016;100(1):1–8.
Purnamasari Y. Hubungan Merokok Dengan Angka Kejadian Tuberkulosis Paru di RSUD Dr. Moewardi Surakarta. 2010.
Sebayang YH. Hubungan Antara Merokok Dengan Kejadian TB Paru di Medan. 2017.
Febriyantoro MT. Pemikiran Irasional Para Perokok. EKSIS. 2016;11(2):124–39.
Tandang F, Amat ALS, Pakan PD. Hubungan Kebiasaan Merokok Pada Perokok Aktif dan Pasif dengan Kejadian Tuberkulosis Paru di Puskesmas Sikumana Kota Kupang. Cendana Med J. 2018;15(3):382–90.
Brinkman GL, Coates EO. The Effect of Bronchitis, Smoking, and Occupation on Ventilation. Am Reveiw Respir Dis. 1962;87(5):684–93.
Ayuningtyas GE, Majdawati A. Hubungan Antara Derajat Merokok Menurut Indeks Brinkman Dengan Lesi Pada Foto Thorax. 2013.
Jimenez-Fuentes MA, Rodrigo T, Altet MN, Jimenez-Ruiz CA, Casals M, Penas A, et al. Factors Associated With Smoking Among Tuberculosis Patients in Spain. BMC Infect Dis. 2016;16(486):1–9.
Bai K-J, Lee J-J, Chien S-T, Suk C-W, Chiang C-Y. The Influence of Smoking on Pulmonary Tuberculosis in Diabetic and Non-Diabetic Patients. PLoS One. 2016;11(6).
Sara G, Hanriko R. Efektivitas Activated Charcoal Cigarette Filter Dalam Menurunkan Risiko Kejadian Kanker Paru. Medula. 2017;7(5):9–13.
Zhang R, Chen L, Cao L, Li K-J, Huang Y, Luan X, et al. Effects of Smoking on The Lower Respiratory Tract Microbiome In Mice. Respir Res. 2018;19(253):1–15.
Murakami D, Kono M, Nanushaj D, Kaneko F, Zangari T, Muragaki Y, et al. Exposure to Cigarette Smoke Enhances Pneumococcal Transmission Among Littermates in an Infant Mouse Model. Front Cell Infect Microbiol. 2021;
Hunter RL. The Pathogenesis of Tuberculosis: The Early Infiltrate of Post-primary (Adult Pulmonary) Tuberculosis: A Distinct Disease Entity. Front Immunol. 2018;9:1–9.
Folga S, Pansare VM, Camero LG, Syeda U, Patil N, Chaudhury A. Cavitary lung lesion suspicious for malignancy reveals Mycobacterium xenopi. Respir Med Case Rep. 2018;23:83–83.
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