Direct Medical Costs Related To Clinical Outcomes And Patterns Of Ischemic Stroke Drug Therapy In Panti Rapih Hospital Yogyakarta


  • Muslimah Faculty of Medicine , Universitas Muhammadiyah Semarang
  • Nina Anggraeni Noviasari Faculty of Medicine , Universitas Muhammadiyah Semarang
  • Nandhini Lawrence Anantaizaldy Student of Faculty of Medicine , Universitas Muhammadiyah Semarang



This study aimed to analyze clinical outcomes related to direct
medical cost and the pattern of drug therapy. This was an
analytical observational study with retrospective and concurrent
data through observation from the perspective of the hospital. A
total of 42 stroke ischaemic patients were enrolled in this study.
Data were collected with a period of 1 year after the first stroke
occurrence, which began on May 15th, 2019 until June 15th, 2020.
Data sources used in this study include medical records, financial
data, and drug data from pharmacies. Data were analyzed using
the Mann-Whitney U test and the Kruskal-Wallis test. This study
findings showed the highest sociodemographic data on age 41-70
years (54,76%), male (59,52%), length of stay of 5-10 days
(66,60%), comorbid of hypertension (88,10%), complication of
urinary tract infection (19,05%), CCI 3-5 (85,71%), condition at
hospital admission of hemiparesis (83,72%), and Antiplatelet drug
therapy (90,48%). Clinical outcomes of disability mostly occurred
in males (59,52%), age 41-70 years (54,76%), and length of stay of
5-10 days (66,67%). There were 48 events of clinical outcome
including 14,29% recurrent stroke and disability (n=6), 100%
disability (n=42) and no mortality (n=0). Recurrent stroke and
disability were not associated with a direct medical cost per year,
neither inpatient nor outpatient cost. This might be due to the
severity of stroke at the hospital admission which not be considered
in this study. In conclusion, this study’s findings could be used as
consideration in the determination of health policy, health
insurance, and data source for pharmacoeconomic.


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How to Cite

Muslimah, Nina Anggraeni Noviasari, & Nandhini Lawrence Anantaizaldy. (2022). Direct Medical Costs Related To Clinical Outcomes And Patterns Of Ischemic Stroke Drug Therapy In Panti Rapih Hospital Yogyakarta . International Journal of Health and Pharmaceutical (IJHP), 2(2), 259–274.