Tuberculosis Infection In Women

Authors

  • Izhar Fitrah Ahmad Faculty of Medicine, Universitas Muslim Indonesia, Makassar, Indonesia
  • Edward Pandu Wiriansya Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Muslim Indonesia
  • Andi Puspa Ratu Department of Internal Medicine, Faculty of Medicine, Universitas Hasanuddin, Bhayangkara Makassar Hospital, Makassar, Indonesia

DOI:

https://doi.org/10.51601/ijhp.v5i1.406

Abstract

The increasing number of deaths due to tuberculosis has triggered the national tuberculosis control program to continue to intensify, accelerate, extend and innovate the program.7A holistic approach must be taken in order to improve tuberculosis control and identify various risk factors associated with tuberculosis infection. The Global Tuberculosis Report 2018 reported that 90% of tuberculosis sufferers are adults and 10% are children (<15 years). Figure 1 shows tuberculosis sufferers worldwide, 64% are men and 36% are women with a ratio of 2:1. In Indonesia, data also shows that tuberculosis is more common in men than women. The high prevalence in men shows that the level of men accessing tuberculosis services is higher than women. Differences in social roles between men and women can also affect risk factors for access to health services. In women, access to tuberculosis treatment and prevention services is more difficult than in men. This is because family members do not want to pay for women's health services. Women's health in the family is considered less important than male family members. Tuberculosis problems also occur in vulnerable populations, namely pregnant women and women with tuberculosis-HIV. A fairly high mortality rate occurs in women with tuberculosis-HIV. In pregnant women, transmission of tuberculosis germs to the fetus occurs, so that the fetus can have latent tuberculosis. Understanding tuberculosis disease in women can help the target of eliminating tuberculosis by 2030. Gender equality and active participation of women in the planning, implementation, and health care processes can be an effective way to overcome the problems of difficulty in accessing tuberculosis services, stigma and discrimination, and various existing barriers.

References

. Ministry of Health of the Republic of Indonesia. Regulation of the Minister of Health of the Republic of Indonesia Number 67 of 2016 concerning the prevention of tuberculosis with the grace of God Almighty. 2016;1–163.

. World Health Organization. Global tuberculosis report 2018. 2018. 265 p.

. Global tuberculosis report 2023 [Internet]. 2023. Available from: https://iris.who.int/.

. World Health Organization. Tuberculosis in women. World Health Organization. Geneva; 2015.

. Ministry of Health of the Republic of Indonesia. Indonesian Health Profile 2018. 2018. 496 p.

. United Nations Development Programme. Discussion Paper: Gender and Tuberculosis. 2015;(December).

. Das J, Kwan A, Daniels B, Satyanarayana S, Subbaraman R, Bergkvist S, et al. Use of standardized patients to assess quality of tuberculosis care: A pilot, cross-sectional study. Lancet Infect Dis. 2019;15(11):1305–13.

. The Global Fund. Tuberculosis, Gender and Human Rights. Geneva; 2017.

. Perumal R, Naidoo K, Padaayatchi N. TB epidemiology: where are the young women? Know your tuberculosis epidemic, know your response. BMC Public Health. 2018;18(1):417.

. Dodd PJ, Looker C, Plumb ID, Bond V, Schaap A, Shanaube K, et al. Age- and Sex-Specific Social Contact Patterns and Incidence of Mycobacterium tuberculosis Infection. Am J Epidemiol. 2015 Dec 8;183(2):kwv160.

. Horton KC, MacPherson P, Houben RMGJ, White RG, Corbett EL. Sex Differences in Tuberculosis Burden and Notifications in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis. PLoS Med. 2016;13(9):1–23.

. Harahap, et, all, Macrozoobenthos diversity as anbioindicator of the water quality in the Sungai Kualuh Labuhanbatu Utara, AACL Bioflux, 2022, Vol 15, Issue 6.Miele K, Bamrah Morris S, Tepper NK. Tuberculosis in Pregnancy. Obstetrics and Gynecology. 2020 Jun 1;135(6):1444–53.

. Harahap, A., et all ( 2021), Monitoring Of Macroinvertebrates Along Streams Of Bilah River International Journal of Conservation Sciencethis link is disabled, 12(1), pp. 247–258.Krishnan L, Akande T, Shankar A V., McIntire KN, Gounder CR, Gupta A, et al. Gender-Related Barriers and Delays in Accessing Tuberculosis Diagnostic and Treatment Services: A Systematic Review of Qualitative Studies. Tuberc Res Treat. 2014;2014:1–14.

. Laia, O. ., Lestari Nasution, S. ., & Ginting, . J. . (2023). Evaluation Of The Implementation Of Primary Care (P-Care) Application At Puskesmas Onolalu Nias Selatan In 2022. International Journal of Health and Pharmaceutical (IJHP), 3(4), 629–636. https://doi.org/10.51601/ijhp.v3i4.224

. Chang SH, Cataldo JK. A systematic review of global cultural variations in knowledge, attitudes and health responses to tuberculosis stigma. International Journal of Tuberculosis and Lung Disease. 2014;18(2):168–73.

. Kurniawan R, Ilmu P, Kurniawan P. Health Program for Lifelong Female Prisoners.

. P GSMMRBRTXV. Socio-economic impact of parental tuberculosis on children. ST -. Indian Journal of Tuberculosis. 2001;48(2):91–4.

. Nhamoyebonde S, Leslie A. Biological Differences Between the Sexes and Susceptibility to Tuberculosis. Journal of Infectious Diseases. 2014 Jul 15;209(suppl 3):S100–6. 6905-25002-1-PB.

. Schurz H, Kinnear CJ, Gignoux C, Wojcik G, van Helden PD, Tromp G, et al. A Sex-Stratified Genome-Wide Association Study of Tuberculosis Using a Multi-Ethnic Genotyping Array. Genet Front. 2019;9.

. Chavez K, Ravindran R, Dehnad A, Khan IH. Gender biased immune-biomarkers in active tuberculosis and correlation of their profiles to efficacy of therapy. Tuberculosis. 2016;99:1724.

. Schurz H, Salie M, Tromp G, Hoal EG, Kinnear CJ, Möller M. The X chromosome and sex-specific effects in infectious disease susceptibility. Hum Genomics. 2019;13(1):2.

. Dibbern J, Eggers L, Schneider BE. Sex differences in the C57BL/6 model of Mycobacterium tuberculosis infection. Sci Rep. 2017 Dec 8;7(1):10957.

. Vázquez-Martínez ER, García-Gómez E, Camacho-Arroyo I, González-Pedrajo B. Sexual dimorphism in bacterial infections. Biol Sex Differ. 2018;9(1):27.

. Yang Z, Huang YCT, Koziel H, de Crom R, Ruetten H, Wohlfart P, et al. Female resistance to pneumonia identifies lung macrophage nitric oxide synthase-3 as a therapeutic target. Elife. 2014 Oct 15;3.

. Orme IM, Robinson RT, Cooper AM. The balance between protective and pathogenic immune responses in the TB-infected lung. Nat Immunol. 2015;16(1):57–63.

. Rafal Jaleel Al-Saigh. The Impact of Tuberculosis on Immunomodulatory Markers: A Clinical Study. Medical Journal of Babylon. 2017;14(3):567–76.

. Botha MH, Van der Merwe FH. Female genital tuberculosis. South African Family Practice. 2008;50(5):12–6.

. Jai B. Sharma, Sona Dharmendra, Shefali Agarwal ES, Department. Genital tuberculosis and infertility. Fertility Science and Research. 2016;3(1).

. Agarwal N, Gupta M, Agrawal A. Evaluation of genital tuberculosis as a cause of female infertility in a tertiary care hospital in North India. Int J Community Med Public Health. 2018 Dec 24;6(1):386.

. Efared B, Sidibé IS, Erregad F, Hammas N, Chbani L, El Fatemi H. Female genital tuberculosis: a clinicopathological report of 13 cases. J Surg Case Rep. 2019 Mar 1;2019(3).

. Migliori Graham Duarte, Raquel Rendon, Adrian GBB, editors. Tuberculosis. European Respiratory Society; 2018. 474 p.

. Yusuf A, Sari I, Studi P, Dokter P, Medis F, Lampung U, et al. Management in Pregnancy with Pulmonary Tuberculosis. 2018;5:622–6.

. Wolf B, Krasselt M, de Fallois J, von Braun A, Stepan H. Tuberculosis in Pregnancy – a Summary. Geburtshilfe Frauenheilkd. 2019;358–64.

. Shrestha A, Gautam K, Pyakurel D, Pradhan S, Pant V. Breast tuberculosis, a rare entity. IDCases. 2019;15:e00530.

. Thimmappa D, Mallikarjuna MN, Vijayakumar A. Breast Tuberculosis. Indian J Surg. 2015 Dec;77(Suppl 3):1378.

. Khan R, Charokar K. Primary tuberculosis of the breast: a diagnostic dilemma. International Surgical Journal. 2019 Mar 26;6(4):1392.

Downloads

Published

2025-02-24

How to Cite

Fitrah Ahmad, I., Pandu Wiriansya, E. ., & Puspa Ratu, A. . (2025). Tuberculosis Infection In Women. International Journal of Health and Pharmaceutical (IJHP), 5(1), 165–174. https://doi.org/10.51601/ijhp.v5i1.406