The Relationship Between Medication Adherence Based on the Morisky Medication Adherence Scale 8 (MMAS-8) and the Degree of Disease Activity Based on the Disease Activity Score-28 (DAS28) in Rheumatoid Arthritis Patients at Royal Prima Hospital

Authors

  • Putri Amanda Anggraini Harahap Medical Study Program Faculty of Medicine, Dentistry and Health Sciences Universitas Prima Indonesia,Medan, Indonesia
  • Herlina Yani Pui Phyto Degenerative & Lifestyle Medicine,Universitas Prima Indonesia
  • Andre Budi Depastement of Dermatology and Venerologi,Faculty of Medicine,Dentistry and Health Sciences Universitas Prima Indonesia, Pui Phyto Degenerative & Lifestyle Medicine,Universitas Prima Indonesia,Medan 20118,Indonesia

DOI:

https://doi.org/10.51601/ijhp.v5i4.503

Abstract

Rheumatoid arthritis (RA) poses a major health challenge due to poor medication adherence impacting disease control. This study aimed to analyze the relationship between medication adherence (MMAS-8) and disease activity (DAS28) in RA patients. A quantitative cross-sectional design was employed at RS Royal Prima Medan (May-July 2025), targeting outpatient RA patients with consecutive sampling (n=69). Data were collected using validated MMAS-8 and DAS28-CRP instruments, analyzed via Kolmogorov-Smirnov normality tests and Spearman's correlation. Results showed moderate adherence (47.8%), low disease activity predominant (31.9%), and significant moderate positive correlation (r=0.400, p<0.001). Higher adherence is linked to better disease control. Conclusion: Medication adherence moderately influences RA disease activity; multifaceted interventions are recommended.

 

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Published

2025-11-30

How to Cite

Amanda Anggraini Harahap, P., Yani, H., & Budi, A. (2025). The Relationship Between Medication Adherence Based on the Morisky Medication Adherence Scale 8 (MMAS-8) and the Degree of Disease Activity Based on the Disease Activity Score-28 (DAS28) in Rheumatoid Arthritis Patients at Royal Prima Hospital. International Journal of Health and Pharmaceutical (IJHP), 5(4), 978–984. https://doi.org/10.51601/ijhp.v5i4.503