Effectiveness Of Cream Formulation Of Carrot Seed Oil As Anti-Aging

Authors

  • Musnaini Musnaini Master of Biomedical Science Study Program, Faculty of Medicine, Universitas Prima Indonesia, Sumatera Utara Indonesia.
  • Silvia Fransisca Master of Biomedical Science Study Program, Faculty of Medicine, Universitas Prima Indonesia, Sumatera Utara Indonesia.
  • William Leslie Master of Biomedical Science Study Program, Faculty of Medicine, Universitas Prima Indonesia, Sumatera Utara Indonesia.

DOI:

https://doi.org/10.51601/ijhp.v3i3.170

Keywords:

Skin, Carrot Seed Oil and Anti-Aging.

Abstract

Carrot (Daucus carota L.) is a vegetable plant that has many uses for public health services in the world. Fresh carrots contain water, protein, carbohydrates, fat, fiber, ash, anti-cancer nutrients, natural sugars (fructose, sucrose, dextrose, lactose, and maltose), pectin, glutathione, minerals (calcium, phosphorus, iron, potassium, sodium, magnesium, chromium), vitamins (beta carotene, B1, and C) and asparagine. The purpose of this study was to characterize simplicia and carrot seed oil extract, and to determine the antioxidant activity of carrot seed oil extract with formulations of concentrations of 3%, 6% and 9% seeds on the effectiveness of anti-aging Moisture, Evenness, Pore, Spot and Wrinkle. Carrot seed oil can be formulated in a homogeneous cream dosage form with an oil-in-water emulsion type, pH 6.7-7.7; does not cause skin irritation and is stable on storage for 90 days at room temperature. Carrot seed oil cream with a concentration of 9% showed the best anti-aging effectiveness by increasing water content, reducing skin hardness, shrinking pores, reducing blemishes and reducing wrinkles compared to other cream formulas.

References

Rahmi U, Yunazar M., dan Adlis S. (2013). Profil Fitokimia Metabolit Sekunder dan Uji Aktivitas Antioksidan Tanaman Jeruk Purut (Citrus histrix DC) dan Jeruk Bali (Citrus Maxima (Burm.f.) Merr). Jurnal Kimia UNAND (ISSN No. 2303-3401), hal: 109-114

Putro, S.D. (1998). Agar Awet Muda. Unggaran. Jakarta: PT. Trubus Agriwidy Elexa. Halaman 2,16.

Tjandrawinata, Raymond R. (2011). Anti Aging, Scintific Journal of Pharmaceutical Development and Medical Application., Vol. 24, No. 1.

Zalukhu, M.L., Phyma, A.R., dan Pinzon, R.T. (2016). Proses Menua, Stres Oksidatif, dan Peran Antioksidan. Cermin Dunia Kedokteran. -245. 43(10): 733-736.

Draelos, Z. D., dan Lauren A. Thaman. (2006) Cosmetic Formulation of Skin Care Product. Taylor and Francis Group: New York.

Poerba, A.P. (2012). Panduan Cantik Untuk Remaja. Yogyakarta: Hanggar Kreator.

Mondal, S.C. (2015). Aging and Potential Anti-Aging Phytochemicals: An Over view. Review Article. World Journal of Pharmacy and Pharmaceutical Science. 4(1): 426-454.

United Soybean Board. (2016). Soybean Oil Innovations. United State: Soyconnection by United Soybean Oil. Hal. 3.

Burke, W, Tracy. (2007). Vitamin E, http://id.svhoong.com, Diakses: 22/08/22

Berdanier, C. D. (1998). Advanced Nutrition: Micronutrient. CLC Press, Florida: 9–19 p.

Winarsi, H. (2007). Antioksidan Alami dan Radikal Bebas: Potensi dan Aplikasinya dalam Kesehatan. Yogyakarta: Kanisius.

Jukka T. Salonen, Kristiina Nyysso¨nen, Riitta Salonen, Elina Porkkala-Sarataho, Tomi-Pekka Tuomainen, Ulf Diczfalusy and Ingemar Bjo¨rkhem (1997). Lipoprotein Oxidation and Progression of Carotid Atherosclerosis. Circulation. Vol.95, No.4: 840–845. https://doi.org/10.1161/01.CIR.95.4.840

Ditjen POM. (1995). Farmakope Indonesia. Edisi Keempat. Jakarta: Departemen Kesehatan RI. Halaman 6, 7, 72, 596.

Rukmana. (1995). Bertanam Wortel. Yogyakarta: Kanisius.

Dalimartha, S. (2001). Atlas, Tumbuhan Obat Indonesia. Jakarta: Trubus Agriwidya.

Staniszewska M & Kula, J. (2001). Composition Of the Essential Oil from Wild Carrot Umbels (Daucus Carota) Growing in Poland. Journalof Essential Oil Resources. Taylor & Francis.Vol.13, Issue 6, pp. 439-441. https://doi.org/10.1080/10412905.2001.9699720

Sarwadi, S. (2014). Buku Pintar Anatomi Tubuh Manusia. Jakarta: Dunia Cerdas. Halaman :75-77.

Putra, B. M., dan Waluyo, S. (2010). The Book of Anti Aging Rahasia Awet Muda Mind, Body, Spirit. Jakarta: PT. Elex Media Komputindo. Halaman 2,3,5,6

Noormindhawati, L. (2013). Jurus Ampuh Melawan Penuaan Dini. Jakarta: PT. Elex Media Komputindo. Halaman 2,4,5

Djuanda, Adhi. (2007). Ilmu Penyakit Kulit dan Kelamin, Edisi 5 Bagian Ilmu Penyakit Kulit dan Kelamin. Fakultas Kedokteran Universitas Indonesia: Jakarta.

Mulyawan, D., dan Suriana, N. (2013). A-Z Tentang Kosmetik. Jakarta: Elex Media Komputindo. Halaman 16-17.

Reynold, James EF, (1982). Martindale The Extra Pharmacopeia, Twenty-eight edition. London. The pharmaceutical press: The Pharmaceutical Press. Hal: 45,788

Chatterjee, K., Hall, K., dan Tell, S. (2011). Glycerol to Propylene Glycol. Philadelpia: Pen Libraries. Halaman 6.

Lieberman, A.H., Lachman L., dan Kanig, J.L. (1994). Teori Dan Praktek Farmasi Industri. Edisi kedua. Jakarta: UI Press. Halaman 110, 1102, 1105, 1092, 1292.

Aramo. (2012). Skin and Hair Diagnosis System. Sungnam: Aram Huvis Korea Ltd. Halaman 1-10

Young, A., (1972) Practical Cosmetic Sciensce, Mills & Boon Limited: London, pp. 17-21, 53-55, 102.

Pratomyot, J., Srivilas, P., Noiraksar, T., 2005, Fatty Acids Composition of 10 Microalgal Species, Songklanakarin, Journal Scoence Technology, Vol.27, No.6: 1179 – 1187.

Depkes RI. (1985). Cara Pembuatan Simplisia. Jakarta: Departemen Kesehatan Republik Indonesia. Halaman 5.

Balsam, M. S., SD Gerson, MM Rieger, E Sagarin, Sj Strianse. (1972). Cosmetics: Science and Technology. New York (US): Jhons Wiley.

Rawlins, E.A. (2003). Bentley’s Textbook of Pharmaceutics. Edisi Kedelapan. Eastbourne. Edisi Ke-enam. London: Pharmaceutical Press. Halaman 75.

Ansel, H.C. (1989). Pengantar Bentuk Sediaam Farmasi. Edisi Keempat. Jakarta: Universitas Indonesia. Halaman 158-159, 162

Wasitaatmadja, S.M. (1997). Penuntun Ilmu Kosmetik Medik. Jakarta: UI Press. Halaman 58,62,111-120

Wille, J.J & Kydonieus, A., (2003) Palmitoleic Acid Isomer (C16:1 delta 6) in Human Skin Sebum is Effective Against Gram-Positive Bacteria, Skin Pharmacol Appl Skin Physiol, 16(3): 87-176

Anonim, (2003) www.kompas.co.id/kesehatan/news. Diakses pada Tanggal 17 Desember 2018, jam 20.00

Oresajo C, Pillai S, Manco M, Yatskayer M, McDaniel D. (2012) Antioxidants and The Skin: Understanding Formulation and Efficacy. Dermatologic Therapy. 25(3):252-259. DOI: 10.1111/j.1529-8019.2012.01505.x

Yaar, M & Gilchrest, BA, (2007) Photoaging: Mechanism, Prevention and Therapy, British Journal of Dermatology, Vol. 157, 2007 ; pp. 874-7.

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Published

2022-12-04

How to Cite

Musnaini, M., Fransisca, S. ., & Leslie, W. . (2022). Effectiveness Of Cream Formulation Of Carrot Seed Oil As Anti-Aging. International Journal of Health and Pharmaceutical (IJHP), 3(2), 331–340. https://doi.org/10.51601/ijhp.v3i3.170

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