Comparison of Hemolysis Events and Hematocrit Quality in Leucodepleted (In Line) and Leucodepleted (Bedsite) Clinical Transfusions
DOI:
https://doi.org/10.51601/ijhp.v3i3.176Abstract
Blood transfusions no longer provide all the blood components but only provide the necessary blood components. We aim to determine whether there is a comparison of hemolysis events and hematocrit quality in leucodepleted (In Line) and leucodepleted (Bedsite) clinical transfusions. This study was an analytic study with a cross-sectional design to compare hemolysis events and hematocrit quality in leucodepleted (In Line) and leucodepleted (Bedsite) clinical transfusions. We obtained sample data in this study divided into 2 groups, namely the group with leucodepleted in line and the group with leucodepleted bedsite inclusion and exclusion criteria of 58 samples.We found that the incidence of hemolysis after leucodepleted (in line) was 0% and leucodepleted (bedsite) was 0.02%, where the standard percentage of blood hemolysis was <0.8%, the hemolysis incident after the production of the two products was very small. While the hematocrit before and after leucodepleted decreased by 35.91% in leucodepleted (in line) and 33.33% in leucodepleted (bedsite). There is a comparison of the incidence of leucodepleted (In Line) and leucodepleted (Bedsite) hemolysis. Where the incidence of leucodepleted (in line) hemolysis is not found, so the leucodepleted (in line) blood component has good quality. There is a comparison of the quality of leucodepleted (In Line) and leucodepleted (Bedsite) hematocrit.
References
Artikel Kesehatan (2020), “Transfusi Darah: Manfaat dan Resikonya untuk Pasien”. https://rs-soewandhi.surabaya.go.id/transfusi-darah-manfaat-dan-resikonya-untuk-pasien/, diakses Oktober 14, 2022.
Isbister JP, Shander A, Spahn DR, Erhard J, Farmer SL, Hofmann A. (2011) Adverse Blood Transfusion Outcomes: Establishing Causation. Transfusion Medicine Reviews Volume 25, Issue 2, April 2011, Pages 89-10. https://doi.org/10.1016/j.tmrv.2010.11.001
Musallam KM, Tamim HM, Richards T, et al. (2011) Preoperative Anaemia and Postoperative Outcomes in Non-Cardiac Surgery: A Retrospective Cohort Study. Lancet Volume 378, Issue 9800, 15–21 October 2011, Pages 1396-1407. https://doi.org/10.1016/S0140-6736(11)61381-0
Bernard AC, Davenport DL, Chang PK, Vaughan TB, Zwischenberger JB. (2009). Intraoperative Transfusion Of 1 U To 2 U Packed Red Blood Cells Is Associated with Increased 30-Day Mortality, Surgical-Site Infection, Pneumonia, And Sepsis in General Surgery Patients. Journal of the American College of Surgeons. Volume 208, Issue 5, May 2009, Pages 931-937.e2. https://doi.org/10.1016/j.jamcollsurg.2008.11.019
Vincent JL, Baron JF, Reinhart K, et al. (2002). Anemia And Blood Transfusion in Critically Ill Patients. JAMA 2002; 288: 1499–507. doi:10.1001/jama.288.12.1499
Klein H. (2005), Mollison’s Blood Transfusion in Clinical Medicine. 11th Edition. United Kingdom: Blackwell Publishing.
Bakta IM. (2006). Hematologi Klinik Ringkas. Jakarta: EGC
Aru S. (2014). Ilmu Penyakit Dalam: Anemia Hemolitik Akibat Transfusi. Jakarta: Interna Publishing.
Savage WJ, et.al. (2011). Allergic transfusion reactions to platelets are associated more with recipient and donor factors than with product attributes. The Journal Off AABB Transfusion. 51(1) :1716-1722. https://doi.org/10.1111/j.1537-2995.2010.03009.x
Weinstein R. (2016). Red Blood Cell Transfusion: A Pocket Guide for the Clinician. American Society of Hematology.
Akbar TI. 2014. Kualitas dan Kejadian hemolisis Packed Red Cell (PRC) Washed Erythrocyte dan Leukodepleted (In-Line) dalam Transfusi Klinis. Journal Indon Med Assoc. 64 (10): 451-455.
Kumar H, et.al. (2006). Leucodepletion and Blood Product. Medical Journal Armed Forces India. 62(2):174-177.
Srihartaty, Yuyun Siti Maryuningsih Soedarmono, Pustika Amalia Wahidiyat (2014) Perbedaan Penurunan Jumlah Leukosit dan Sitokin pada Packed-Red Cell dengan Metode Buffy-Coat Depleted dan Modifikasi Bed-Side Leucocyte Filtration. Journal Indonesian Medical Association, Volume: 64, Nomor: 10, Oktober 2014. 2014. http://mki.idionline.org/index.php?uPage=magazine.magazine_article&smod =magazine&sp=public&iddata=24
Samuel O. (2002). Red Blood Cell Hemolysis During Processing. Transfusion Medical. 16: 46-60.
Thelma AP. Emanuela C. (2016). A Comparative Study of the Effect of Leukoreduction and Pre-Storage Leukodepletion on Red Blood Cells during Storage. Frontiers in Molecular Biosciences. 3 (13): 1-9.
Mustafa I, et. Al. (2016). Time Dependent Assessment of Morphological Changes: Leukodepleted Packed Red Blood Cells Stored in SAGM. Biomed Research International. 1-7.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Frisca Novasari Saragih, Hendy Million, Masyitah Masyitah

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.